Packj [1] detects malicious PyPI/NPM/Ruby/PHP/etc. dependencies using behavioral analysis. It uses static+dynamic code analysis to scan for indicators of compromise (e.g., spawning of shell, use of SSH keys, network communication, use of decode+eval, etc). It also checks for several metadata attributes to detect bad actors (e.g., typo squatting).

1. https://github.com/ossillate-inc/packj