paracetamol is unusual in this respect, that the toxic dose is so close to the therapeutic dose, but the benefits outweigh the risks.

after I had dental surgery, I took paracetamol and ibuprofen in alternate doses every 4h - I would have been in screaming pain if I couldn't have both as an option.

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kelnos 5 days ago | parent [-]

Maybe by FDA-type standards, 4x is "close", but to me, I would think it absurd to take 4x the recommended dose of something unless directed to by a doctor.

I was recently prescribed 800mg ibuprofen for an injury, where 200mg is the standard OTC dose, and I even questioned that.

	▲	exe34 5 days ago \| parent [-]
		you'd be surprised how casual some people are with doses. my old grandma had a big bag of medication she had collected over the years and occasionally she'd sit down and pick a couple like smarties and gulp them down. when my dad decided to step in, he took her to a doctor to get a full review and confiscate the bag.