Yes. The obvious solution is to either design your politico-economic system that big players never emerge, or are such that they don't have incentives to corrupt (eg. SOE).

Another example of the latter, is that large companies should always be majority owned by their employees in a 1/N fashion. The idea being that even if such players try to rent-seek, at least the rent is being extracted in favor of normal people rather than a small class of rich people.