Drug addicts, patients and recreational users start to increase the dosage and chase the high.

Others don't chase the high at all, but remember the state of mind and simply tune their brains to respond with said high on command whenever the chemistry in the brain fulfills the conditions, which can happen without taking the drug at all.

I don't see a loop there; I see different levels of awareness, consciousness and needs.

It's also what I think when I hear Hofstadter or (high-)functioning people talking about being "strange loops". ... use some of your opportunities, peace of mind and resources to sue people (you can probably come up with entire lists...) and the "strange loop" will break immediately.

Some people edge for days, others had to use various toys and stimuli before getting off since youth.