There are much better solutions for the same problems, but not in Python. If you really need such high throughput you'd move to Go, the JVM or Erlang/Elixer depending on the kind of workload you have rather than to much around with Python on something that it clearly was never intended to do in the first place. It is amazing they got it to work as well as it does but the impedance mismatch is pretty clear and it will never feel natural.

Elixir is a really nice replacement for a lot of places where you could you python but don't absolutely have to, particularly anything web related. You get a lot more out of the same machine with code that's similarly readable for building HTTP APIs.