Isn't the conventional wisdom "at least 2 backups, one offsite"? My lab gets by with 2 copies for most of our data: one on our Synology NAS and one mirrored to Box.

With the size of data we're dealing with, loading everything from cloud all the time would slow analyses down to a crawl. The Synology is networked with 10G Ethernet to most of our workstations.