There's that aphorism that goes: people who thought the epitome of technology was a steam engine pictured the brain as pipes and connecting rods, people who thought the epitome of technology was a telephone exchange pictured the brain as wires and relays... and now we have computers, and the fact that they can in principle simulate anything at all is a red herring, because we can't actually make them simulate things we don't understand, and we can't always make them simulate things we do understand, either, when it comes down to it. We still need to know what the thing is that the brain does, it's still a hard question, and maybe it would even be a kind of revolution in physics, just not in fundamental physics.

>We still need to know what the thing is that the brain does

Yes, but not necessarily at the level where the interesting bits happen. It’s entirely possible to simulate poorly understood emergent behavior by simulating the underlying effects that give rise to it.