Does America have the economic, social, and industrial resources to wage such warfare with the cartels?

America has spent trillions on two failed wars in the past 25 years, and lacks the economic capability to produce artillery shells to aid Ukraine.

At the same time it needs to build up industrial capacity to defend against an impending war in the pacific and it doesn't seem to be able to do that.

It is unlikely that engaging in all out war with the cartels is a viable path at this time.