0.41 included some "non-colliding keybind" option, and you can clear-defaults in the config now, so this issue might be fixed. I haven't tested it but I recall seeing news about it.

Last I tried it the bind issue and performance were sort of blockers for me, but it looks like both of those are moving forward.

https://github.com/zellij-org/zellij/releases/tag/v0.41.0