For hobby use I have found it best to do circuit design and simulation in different pieces of software. LTspice for simulation and KiCad or EasyEDA for PCB design.

Fully agree that your mind has to be a particular type of broken to click with all of these. I love LTspice for its simulation tools, for example the ability to vary a component value over time in a transient simulation, but it is a software that fights you at every turn when you try to learn it.