Im investigating creating a nattokinase overexpression strain for fun. This is my second home-brewed food GMO!

Basically, nattokinase is an enzyme made by natto (Japanese fermented soybeans). It’s been show clinically to help against blood clots. Unfortunately, the clinical dose is 5x the quantity in a serving of natto.

That’s too much natto to eat! So I’m working to genetically engineer a normal, typical natto strain to just over express that one enzyme, so 1 serving == 1 clinically relevant dose

My last was genetically engineering yeast to produce grape aroma, then baking bread. Was great fun feeding people it. I want to eventually throw GMO dinner parties in SF, but only with GMOs I’ve created with my own hands

Coolest project I've seen in this thread so far.