Of course there is, but when the perspective being asked is, "What's it like to raise a child with DS?" the only people who validly have an opinion are parents of kids with DS.

A different N==1, a friend and coworker of mine had a son with DS at 23. He's now the oldest of six children. They're doing great, and he's a terrific big brother.

I think the studies matter because N needs to equal more than 1 to get a sense of how it goes for the people who do it.