Yeah.

I personally ran into the legacy setup issue for running vanilla Wireguard for my setup before Tailscale is a thing and have to manually manage keys, routing and DNS.

But one thing Tailscale has that annoyed me is that they are using 100.64 CGNAT addresses (which is more RFC-compliant) but conflicts with one of my cloud service provider's pre-configured DNS, NTP and software mirrors setup. Using it became more or less messy for this reason.

You can change what IP addresses it uses: https://tailscale.com/kb/1304/ip-pool