My practice in writing assembly is so lost by now that it's not much different than if I never learned it. Yet, it's not really a problem.

What is different about LLM-created code is that compilers work. Reliably and universally. I can just outsource the job of writing the assembly to them and don't need to think about it again. (That is, unless you are in one of those niches that require hyper-optimized software. Compilers can't reliably give you that last 2x speed-up.)

LLMs by their turn will never be reliable. Their entire goal is opposite to reliability. IMO, the losses are still way higher than the gains, and it's questionable if this is an architectural premise that will never change.