I'm not sure of the exact reasons but you don't really see vapor-compression heat pumps in the tens- to low-hundreds-of-watts range. So I suspect there are some scaling factors where the reduced size/noise/complexity of a solid-state device starts to be more important than the extra energy that it uses.

I think most of the commercial bed cooling systems are thermoelectric (ChiliPad, Eight Sleep) and they seem to work fine, but by the time you get to the scale of a small fridge or dehumidifiers the products are generally awful.

machining metal parts to tight tolerances when they're only a millimeter wide is awfully expensive.

But making tiny things with lithography is really cheap (in volume).

The middle ground is what one needs for a 10 watt vapor compression pump. And to my knowledge nobody has built a 1 watt pump with lithography - although an array of electrostatic scroll compressors does look like it could work.