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hinkley a day ago

Oh I know we are trying to genomically test them for oncology research and potential treatment plans, but do they do paternity tests on them?

I was trying to remember which mammal in Australia gets tumors from fighting, and I found a reference to a mother getting melanoma from her daughter. It’s unclear to me whether the cancer transmission was rare or the identification is rare.

rflrob a day ago | parent | next [-]

There’s very often a comparison to the somatic (i.e. non-cancer) genome of the same patient. It’s a great way to quality control that there wasn’t some sample mixup in the lab.

Transmission of cancer is rare in humans—if it were not, it would make someone’s career to find many cases of it. While we can’t say that all sheep are white, we’ve looked at enough of them to say that black sheep are not common. Furthermore, it’s very clear how the Tasmanian devil cancer is spread—it’s around the mouth while they are biting each others faces; it’s not as obvious how one would spread most human cancers.

Kalanos an hour ago | parent | next [-]

somatic = cancer. germline = inherited.

hinkley 21 hours ago | parent | prev | next [-]

Oh that makes sense. I forgot about differential analysis.

jjtheblunt 20 hours ago | parent | prev [-]

Is HPV an example?

cogman10 20 hours ago | parent [-]

Not really. It's a virus that can cause cancer and not the cancer itself.

dekhn a day ago | parent | prev | next [-]

tasmanian devils [edit: I guess you already said that] https://en.wikipedia.org/wiki/Devil_facial_tumour_disease

hinkley 21 hours ago | parent [-]

Yup. Link is handy though. Someone will post it to the front page in 14 hours :)

tdullien 5 hours ago | parent | prev [-]

Tasmanian devils.