I use Hammerspoon for this and it's super configurable via Lua--open some URLs with Chrome profile 1, some with profile 2, some in incognito, open normal Spotify links with the Spotify app, normal Zoom links with Zoom (skip opening a tab that then opens the zoom:// link), etc.

For Google Drive links I open a picker that lets me choose from two chrome profiles and incognito.

Would you mind sharing some tips on how to set that up? A code snippet or a link to the relevant docs would be super helpful.

cool