I don't think so. This model kills the need for Flux, ComfyUI, LoRAs, fine tuning, and pretty much everything that's come before it.

This is the god model in images right now.

I don't think open source diffusion models can catch up with this. From what I've heard, this model took a huge amount of money to train that not even Black Forest Labs has access to.

ComfyUI supports 4o natively so you get the best of both worlds, there is so much that you can't do with 4o because there's a fundamental limit on the level of control you can have over image generation when your conditioning is just tokens in an autoregressive model. There's plenty of reason to use comfy even if 4o is part of your workflow.

As for LoRAs and fine tuning and open source in general; if you've ever been to civit.ai it should be immediately obvious why those things aren't going away.

95% of what I do with image models is train LoRAs/finetune family and friends and create images of them.

Sure, I can ghiblify specific images of them on this model, but anything approaching realistic changes their looks. I've also done specific LoRAs for things that may or may not be in their training data, such as specific movies.