In my experience, the compiler, compute drivers, and HIP runtime work fine for all modern AMD GPUs. The only parts of the stack that don't run on all GPUs are the math and AI libraries. And that is mostly because AMD isn't building and testing those libraries for unsupported GPUs. The actual work required to enable functional support was straightforward enough that I ported them myself when packaging the libraries for Debian. Though, I had a lot of help on the testing.

See the Debian Trixie Supported GPU list: https://salsa.debian.org/rocm-team/community/team-project/-/...