As a counterpoint, I pretty much always split into 2+ windows. A 2-window setup is a code + terminal setup with shortcuts to run commands on the terminal(s). On more complex projects there are typically more than one terminal windows.

My org-mode emacs instance for note taking is split into quite a few windows: ongoing work task(s), generic "today's scratch pad", various topical notes files, etc.

On the posted topic: I don't know whether the transposition would be useful for me though - as the layout is set up by screen orientation then only a 180 degree turn would make sense.