Depends on the use case.

If you’re a data viz team and do this all the time, and everyone knows or is willing to learn D3, then sure. Otherwise, if you just need to add a graph to your website, you may find it slows you down and makes code less maintainable.

I personally find it confusing and as others mentioned I can forget how it works over time, though I admire it. I don’t think I could jump in and edit D3 code today without careful study, any more than I could jump in and edit Perl code. Echarts/Highcharts etc. are much more intuitive.