Hmm, no way to turn off the sticky keys shortcuts and similar; I hit those by accident _constantly_ on new machines.

You could achieve this with the “Run Custom Scripts” option and the appropriate Registry values:

    HKEY_CURRENT_USER\Control Panel\Accessibility\StickyKeys\Flags="506"

    HKEY_CURRENT_USER\Control Panel\Accessibility\MouseKeys\Flags="58"

    HKEY_CURRENT_USER\Control Panel\Accessibility\ToggleKeys\Flags="58"