I think Nue just puts you in the mindset of trying to keep the codebase as small and lightweight as possible. I wanted to rebuild my website with Nue and there was something telling me to avoid Motion, Tailwind CSS, etc. This philosophy can actually prove very helpful in the long term, however I feel that by using Nue you're really compromising on DX (development is much slower), although that might be because I'm not so familiar with creating websites without a framework. In any case, it's definitely worth a try.