Hi hi.

You may be interested in the VITALITY study out of China from 2022. 400+ people given FOLFOX + Avastin (standard of care, first line for colorectal cancer) vs FOLFOX + Avastin + high dose Vit C.

https://pubmed.ncbi.nlm.nih.gov/35929990/

Roughly showed no change for the overall population, but a significant increase in progression free survival for folks with RAS mutations.

As someone with a stage 4 colorectal cancer with a RAS mutation, this is interesting to me!

Hey.

Sorry about your diagnosis.

Thanks for sharing. This is an interesting, though somewhat disappointing, paper.

One thing I didn't get while reading it was the specific blood concentration achieved. I noticed they mentioned 12 rounds with 3 infusion days and 1.5g/kg. I'm assuming they injected that amount daily.

I noticed they injected over a period of 3 hours. To my knowledge the half life of vitamin c in blood is only 2 hours. I wonder if the concentration of vitamin c ever got sufficiently high to induce apoptosis.

At IV clinics near me they offer 75g bags of vitamin c on the website that are administered over an hour. I bet you could go back to back and get a higher concentration. In the same trip I wonder if you could get something fun - an IV clinic near me offers a nootropic, methylene blue, might charge you up for a day of studying cancer treatments.

One final idea I've had, not sure how useful it is to you, is that you can an at home ultrasound for a few thousand dollars. You should be able to use it to see your intestines and the tumors growing inside. You could use this to monitor your own treatment - i.e. take daily pictures and examine before and after vitamin c therapy, to see if it does anything.

Best of luck to you. If you want to bounce ideas for DIY cancer treatments off of anyone let me know and we can exchange emails.