Neither of the test libraries are specific to unit tests, so I don't quite understand that comment.

That said, there are a lot more issues than just the differences between JSC and V8 - the Bun and NodeJS runtimes, while theoretically exposing the same modules, have a lot of practical differences that are visible in userland code, such as different exceptions, different orderings of queue events, etc. I imagine quite a lot of more complex code depends in some way on platform behaviours like these.