I've been very happy with node:test (and deno:test), but also I migrated from mostly mocha as jest I found difficult to configure, especially without unnecessary bundling configurations as the ESM support among other things was broken for far too long (but mocha delivered it well). Most of my successful uses of jest were out-of-the-box configs in create-react-app and the Angular tools to strip uses of karma and replace them with jest. (Side rant: Seriously whoever thought that karma was a good idea for a test runner? "I love V8 so much I'm using Node's V8 to spin up another headless Chromium's V8 so I can V8 from inside V8." lolsob)