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notamy a day ago

> Subligual methylcobalamin works just as well as the shots

It does not. The cobalamin molecules are quite large and don’t penetrate the sublingual mucosa very well. On top of that, the proteins in saliva that bind to B12s will cause any bound B12 to not absorb sublingually, instead having to wait to make it through the digestive system for intestinal uptake.

Sublingual is still certainly a better option than oral pills, but the injections are preferable in severe cases for a reason.

FollowingTheDao a day ago | parent [-]

> The cobalamin molecules are quite large and don’t penetrate the sublingual mucosa very well.

Absolute nonsense.

Did you even bother to look for one paper on the subject? Here are a few:

https://www.scielo.org.mx/scielo.php?pid=S0034-8376202000060...

https://pubmed.ncbi.nlm.nih.gov/34871525/

https://www.proquest.com/openview/e9a25963dbc92150e420a3a847...