I'm legally blind (I'm very nearsighted, to the point where I need to be within an inch of the screen to see it), and this is basically how I use my computer comfortably. I have my monitor arm mounted to the front of the desk, to the left of my monitor. This allows me to have the monitor slightly out from the front of the desk but still put my hands under it to the keyboard. This does create some awkward situations though, like using a webcam is challenging because I'd need to push my monitor back but then I can't see it! I usually put the camera off to the side on the rare occasions that I need to be on video.