Way to blow up a point into absurd! Nabokov wrote about tiring of specific patterns and cliches obviously

I don't think that is at all obvious from OP's comment. Reading "But his sensitive murderers and soulful prostitutes are not to be endured for one moment" the straightforward interpretation is that the writer doesn't like when a prostitute is represented as soulful.

If the problem is not the soulful prostitutes per se, but something more specific that makes it cliche, I think the quoted phrase could have expressed that better.

pretty cliche itself I'd say. Like a teen who thinks sarcasm is highbrow.