> Simplicity and convenience is what people not only want, but demand.

Hmm, that is not my experience generally. People will take insanely ineffective routes if that is what the system pushes them toward, without taking much offense.

For example, on the topic of health/weight loss: Weight Watchers or yoga classes are huge industries while also being insanely elaborate and expensive ways of eating better and moving your body.

I agree with you that, for example, drugs are currently not a solution to these problems. But what I propose is: they are going to be. And they had better be because there is no other effective solution poised to work at a societal scale. We just can’t help ourselves. “Just eat the salad and walk every day” simply did not do the trick. We tried. While it works on a mechanistic level, of course, it does not work in practice. Blaming people for their inability to fight their nature is just inhumane and not how we usually progress: we fix reality for ourselves.

While it is not impossible to design a society that is healthier (see: Japan), it’s at such odds with our current culture, and societal change is slow. We should certainly get to work on this decades-long project, but we should also treat this like any other health issue that costs billions of life-years and find a more effective intervention.

> Blaming people for their inability to fight their nature is just inhumane

It'd be nice if people didn't have to fight their nature. Our society demands we act in ways that are unhealthy and unnatural. We're forced to sit in chairs 8+ hours a day from very young ages. Children have teachers making sure they stay in their seats, and workers have supervisors enforcing inactivity either in person or using webcams and software. Companies like Amazon insist that their employees piss in bottles or wear diapers because leaving their workstation, even to use a bathroom, will get them fired. The demands of our daily lives and the design of our environments keep us from living the way we've evolved to live and it's normal and should be expected that many people will struggle with that reality more than others.

Either our society and environment needs to change, or our biology and chemistry need to change. Turns out, it's easier to change ourselves than it is to change the massive systems designed by greed and exploitation that we're forced to live in. We'll adapt. Today it's with drugs. Tomorrow it may be genetic manipulation.

I think some people feel strongly about this issue because it seems like giving up on societal change, which IS necessary for many reasons besides just weight. Even if GLP-1 drugs are safe and long term effective for body fat, they are still a band-aid for a deeper problem. The deeper problem is that people feel and express less and less agency and control over their personal lives. This manifests in many forms, such as depression, anger, cynicism, addiction, loneliness, and personal stagnation. Weight loss will do little to improve these measures while the average American watches 4 hours of TV and is devoid of community.

Im hopeful that these drugs can give people a toehold to tackle these deeper issues, and try to emphasize that they are not a panacea.

People are a product of society, and society is a product of people. If we want to live better people will have to change too.