It also decreases gut motility, which helps with the intended effect of appetite suppression. Young healthy people tend to shrug at that. As an old person that takes it right off the menu even before I read about accelerated sarcopenea. Maybe it's the same effect on the peristaltic muscles.

I tried taking it for IBS for that reason.

It worked! Kind of. The first few days after every dose it had the opposite intended effect so it wasn’t worth it.

A bare glp-1 agonist doesn’t, I think, but the weight loss versions are double-acting and do also slow digestion.