I assume this is about adblock. In that case, the PC owner/user's right to control their own hardware takes priority over the content creator's desire to control other people's hardware. Without that fundamental rule, it becomes possible for i.e. John Deere to dictate how you can repair or modify your own equipment, if they allow you to do it at all.

It's unpleasant and I really feel for the content creators whose livelihoods are impacted but we've already seen how bad it is to restrict end users' autonomy.

Adblock is not an issue. He hawks piracy tools.